Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | TLR4 | O00206 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854197 | 0.91 | KMT2A (0.53) | TSHRLTA4HKMT2ASMN1; SMN2GPBAR1 | |
| SCHEMBL11663247 | 0.91 | KMT2A (0.58) | TSHRLTA4HKMT2ASMN1; SMN2 | |
| SCHEMBL18883701 | 0.87 | TSHR (0.51) | TSHRLTA4HTLR4TLR2CYP1A2 | |
| SCHEMBL4397448 | 0.84 | TSHR (0.63) | TSHRLTA4HTLR4TLR2CYP1A2 | |
| SCHEMBL27639866 | 0.83 | CA12 (0.50) | LTA4HGPBAR1CYSLTR2CYSLTR1CYP3A4 | |
| SCHEMBL12125580 | 0.83 | TSHR (0.47) | TSHRLTA4HTLR4TLR2CYP1A2 | |
| SCHEMBL9487844 | 0.82 | TP53 (0.57) | TSHRLTA4HCYP1A2CYP2C19KMT2A | |
| SCHEMBL13536973 | 0.82 | TSHR (0.58) | TSHRLTA4HKMT2APLA2G4BSMN1; SMN2 | |
| SCHEMBL13179955 | 0.81 | KMT2A (0.43) | TSHRTLR4TLR2KMT2ATHRB | |
| SCHEMBL28958950 | 0.81 | TSHR (0.61) | TSHRLTA4HTHRBPLA2G4BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7343073-B2 | Optical members and compositions for producing them | FUJIFILM CORPORATION (JP) | 2008-03-11 | — | — | US | disclosed |
| US-7343073-B2 | Optical members and compositions for producing them | FUJIFILM CORPORATION (JP) | 2008-03-11 | — | — | US | disclosed |
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |