Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 12/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487539 | 1.00 | TSHR (0.50) | TSHRGAAMAPTGPR88L3MBTL1 | |
| SCHEMBL9490034 | 0.89 | MAPT (0.58) | TSHRGAAMAPTGPR88L3MBTL1 | |
| SCHEMBL9490038 | 0.89 | MAPT (0.58) | TSHRGAAMAPTGPR88L3MBTL1 | |
| SCHEMBL10804894 | 0.86 | TSHR (0.48) | TSHRGAAGPR88TAS1R3TAS1R1 | |
| SCHEMBL10804900 | 0.86 | TSHR (0.48) | TSHRGAAGPR88TAS1R3TAS1R1 | |
| SCHEMBL9496762 | 0.86 | GAA (0.59) | TSHRGAAMAPTL3MBTL1ADRB2 | |
| SCHEMBL9488625 | 0.86 | KMT2A (0.55) | TSHRGAAMAPTL3MBTL1ADRB2 | |
| SCHEMBL9488621 | 0.86 | KMT2A (0.55) | TSHRGAAMAPTL3MBTL1ADRB2 | |
| SCHEMBL9487461 | 0.85 | TSHR (0.67) | TSHRGAAMAPTL3MBTL1ADRB2 | |
| SCHEMBL9489444 | 0.85 | TSHR (0.60) | TSHRGAAMAPTL3MBTL1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168043-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1990-11-07 | — | — | EP | claimed |
| US-5236618-A | Liquid crystal phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-17 | — | — | US | disclosed |
| EP-0168043-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1990-11-07 | — | — | EP | disclosed |
| US-4744918-A | Liquid crystal phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-05-17 | — | — | US | disclosed |
| EP-0168043-A2 | Liquid crystal phase | MERCK PATENT GmbH (DE) | 1986-01-15 | — | — | EP | disclosed |