Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30272529 | 1.00 | HTR1B (0.52) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL4289478 | 0.85 | HTR1B (0.59) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL30373629 | 0.81 | MAPT (0.61) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL28676783 | 0.81 | HTR1B (0.55) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL29367279 | 0.81 | MAPT (0.61) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL151449 | 0.81 | MAPT (0.61) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL28602414 | 0.79 | MAPT (0.59) | HTR1BALDH1A1HSD17B10PGRGAA | |
| Methane SCHEMBL28597903 | 0.79 | MAPT (0.59) | HTR1BALDH1A1HSD17B10PGRGAA | |
| 1,2-Dimethoxybenzene SCHEMBL20581614 | 0.79 | CA12 (0.62) | HTR1BALDH1A1HSD17B10PGRGAA | |
| Ammonia Solution, Strong SCHEMBL229215 | 0.79 | MAPT (0.59) | HTR1BALDH1A1HSD17B10PGRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338438-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-07-06 | — | — | US | claimed |
| WO-2022255888-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |
| EP-0273590-B1 | STABILIZATION OF KETAZINE DYES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
| US-4795697-A | WITH POLYVINYLCHLORIDE, PHOTOTHERMOGRAPHY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0194026-B1 | PHOTOTHERMOGRAPHIC STABILIZERS FOR SYRINGALDAZINE LEUCO DYES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0273590-A2 | Stabilization of ketazine dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |
| EP-0194025-A1 | Photothermographic toners | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-09-10 | — | — | EP | disclosed |
| EP-0194026-A1 | Photothermographic stabilizers for syringaldazine leuco dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-09-10 | — | — | EP | disclosed |
| US-4587211-A | Photothermographic stabilizers for syringaldazine leuco dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| US-4585734-A | Photothermographic toners | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
| US-4123282-A | PHTHALAZINE, AROMATIC ACID OR ANHYDRIDE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-10-31 | — | — | US | disclosed |