Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HEXD | Q8WVB3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487269 | 0.90 | TSHR (0.54) | SMN1; SMN2LMNAHPGDTSHRMAPK1 | |
| SCHEMBL7266571 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHPGDTSHRMAPK1 | |
| SCHEMBL21094 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHPGDTSHRMAPK1 | |
| SCHEMBL4620431 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHPGDTSHRMAPK1 | |
| SCHEMBL4620434 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHPGDTSHRMAPK1 | |
| SCHEMBL4620207 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHPGDTSHRMAPK1 | |
| SCHEMBL4620213 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHPGDTSHRMAPK1 | |
| SCHEMBL3231214 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHPGDTSHRMAPK1 | |
| SCHEMBL5374163 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHPGDTSHRMAPK1 | |
| SCHEMBL7427578 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAHPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262393-B1 | DERIVATIVES OF ARYLOXYCARBONIC ACIDS, THEIR PREPARATION AND THEIR USE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-01-07 | — | — | EP | disclosed |
| EP-0262393-A1 | Derivatives of aryloxycarbonic acids, their preparation and their use | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-04-06 | — | — | EP | disclosed |