Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640668 | 0.84 | MAPT (0.57) | MAPTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6432585 | 0.84 | SLC6A4 (0.56) | SLC6A3SLC6A4SLC6A2MAPTSMN1; SMN2 | |
| SCHEMBL29441710 | 0.84 | SLC6A4 (0.56) | SLC6A3SLC6A4SLC6A2MAPTSMN1; SMN2 | |
| SCHEMBL11816175 | 0.83 | GUSB (0.56) | MAPTSMN1; SMN2GAABRAFGSK3B | |
| SCHEMBL6438984 | 0.83 | MAPK1 (0.53) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL10924211 | 0.82 | MAPT (0.56) | MAPTSMN1; SMN2KMT2AGAAPOLB | |
| SCHEMBL5935194 | 0.82 | PTGDR2 (0.54) | SLC6A3SLC6A4MAPTMEN1KMT2A | |
| SCHEMBL15229768 | 0.82 | MYC (0.55) | SLC6A3SLC6A4MAPTSMN1; SMN2MEN1 | |
| SCHEMBL30338973 | 0.82 | PTGDR2 (0.54) | SLC6A3SLC6A4MAPTMEN1KMT2A | |
| SCHEMBL28914441 | 0.82 | POLB (0.57) | MAPTSMN1; SMN2HTTPOLBAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183623-A | A group of benzene sulfonamido benzamide derivatives, and preparation and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-07-03 | — | — | CN | disclosed |
| US-5187168-A | Hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-16 | — | — | US | disclosed |