SCHEMBL9488587

SCHEMBL9488587

CCCCCc1cccc2c1Nc1ccccc1S2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 11/20 0.50
GAA P10253 6/20 0.50
MAPT P10636 6/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ALOX15 P16050 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
BCHE P06276 2/20 0.50
ACHE P22303 2/20 0.50
SNCA P37840 2/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
ALOX12 P18054 1/20 0.50
MAOA P21397 1/20 0.50
CNR1 P21554 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
HTR2C P28335 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30957954 0.99 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL17453909 0.99 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL31441075 0.99 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL30957960 0.99 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL985674 0.99 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL985835 0.99 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL30957964 0.99 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL252565 0.99 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL986417 0.99 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL30957962 0.99 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115572258-A C 2 Preparation method of axial chiral biquinoline framework compound 中国科学院成都有机化学有限公司 2023-01-06 CN claimed
CN-115403522-A Biphenyl quinoline skeleton compound with C2 axis chirality, chiral isomer thereof, preparation method and application thereof 中国科学院成都有机化学有限公司 2022-11-29 CN claimed
CN-115403523-A Biquinoline-aryl phenol framework compound with axial chirality and preparation method and application thereof 中国科学院成都有机化学有限公司 2022-11-29 CN claimed
CN-110407830-A A method of synthesis N- aryl phenothiazine compound UNIV HENAN NORMAL 2019-11-05 CN claimed
US-5178784-A Lubricant compositions THE LUBRIZOL CORPORATION (US) 1993-01-12 US claimed
CN-115572258-A C 2 Preparation method of axial chiral biquinoline framework compound 中国科学院成都有机化学有限公司 2023-01-06 CN disclosed
CN-115403522-A Biphenyl quinoline skeleton compound with C2 axis chirality, chiral isomer thereof, preparation method and application thereof 中国科学院成都有机化学有限公司 2022-11-29 CN disclosed
CN-115403523-A Biquinoline-aryl phenol framework compound with axial chirality and preparation method and application thereof 中国科学院成都有机化学有限公司 2022-11-29 CN disclosed
CN-114133395-A Pyrroloquinazolinone skeleton compound with fluorescence characteristic, preparation method and application 中国科学院成都有机化学有限公司 2022-03-04 CN disclosed
CN-110407830-A A method of synthesis N- aryl phenothiazine compound UNIV HENAN NORMAL 2019-11-05 CN disclosed
CN-110407830-A A method of synthesis N- aryl phenothiazine compound UNIV HENAN NORMAL 2019-11-05 CN disclosed
CN-110407830-A A method of synthesis N- aryl phenothiazine compound UNIV HENAN NORMAL 2019-11-05 CN disclosed
US-5102565-A Containing extreme pressure wear resistant additives and water resistant hydrophobic polymer AMOCO CORPORATION (US) 1992-04-07 US disclosed
US-5000862-A Process for protecting bearings in steel mills and other metal processing mills AMOCO CORPORATION (US) 1991-03-19 US disclosed
US-4986923-A High performance extreme pressure lubricant AMOCO CORPORATION (US) 1991-01-22 US disclosed
WO-1990012079-A1 PROCESS FOR PREVENTING GREASE FIRES IN STEEL MILLS AND OTHER METAL PROCESSING MILLS AMOCO CORPORATION (US) 1990-10-18 WO disclosed
US-4902435-A LUBRICANTS AMOCO CORPORATION (US) 1990-02-20 US disclosed
US-4830767-A MIXTURE OF BASE OIL, POLYUREA THICKENER, CARBONATE, PHOSPHATE; EXTREME PRESSURE, WEAR RESISTANCE AMOCO CORPORATION (US) 1989-05-16 US disclosed
EP-0296362-A2 Lubricating grease, process for its preparation and its use AMOCO CORPORATION (US) 1988-12-28 EP disclosed
EP-0233757-A2 Front-wheel drive grease AMOCO CORPORATION (US) 1987-08-26 EP disclosed