Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.59 |
| ▸ | RELA | Q04206 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487282 | 1.00 | NPC1 (0.59) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9488901 | 1.00 | NPC1 (0.59) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9487784 | 1.00 | NPC1 (0.59) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9487347 | 1.00 | NPC1 (0.59) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9488544 | 1.00 | NPC1 (0.59) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9488421 | 0.95 | NPC1 (0.57) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9488236 | 0.95 | NPC1 (0.57) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9487044 | 0.95 | NPC1 (0.57) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9488107 | 0.95 | NPC1 (0.57) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9488853 | 0.95 | NPC1 (0.57) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255962-B1 | OPTICALLY ACTIVE MESOMORPHIC COMPOUND | CANON KABUSHIKI KAISHA (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-5143643-A | Liquid crystals | CANON KABUSHIKI KAISHA (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0255962-A2 | Optically active mesomorphic compound | CANON KABUSHIKI KAISHA (JP) | 1988-02-17 | — | — | EP | disclosed |