SCHEMBL948915

SCHEMBL948915

C=CC(=O)OCc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.43
ALDH1A1 P00352 4/20 0.43
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HPGD P15428 1/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP12 P39900 1/20 0.39
THRB P10828 3/20 0.37
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3851654 0.98 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3844897 0.98 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3843282 0.96 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL26363010 0.89 TDP1 (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL31115299 0.83 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21244246 0.80 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9416608 0.77 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11350191 0.77 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9106333 0.75 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11692449 0.75 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250328075-A1 PHOTOCURABLE COMPOSITION FOR FORMING AN IMPRINT LITHOGRAPHY TEMPLATE CANON KK (JP) 2025-10-23 US claimed
CN-119161810-A Aviation cable frame-passing protection material, preparation method and aviation cable frame-passing protection strip 安徽省众望科希盟科技有限公司 2024-12-20 CN claimed
CN-112778916-B Special fluorine-containing pressure-sensitive adhesive and preparation method thereof 四川轻化工大学 2023-04-18 CN claimed
CN-115044329-A Special high-performance fluorine-containing silicon pressure-sensitive adhesive and preparation method thereof 四川轻化工大学 2022-09-13 CN claimed
CN-112778916-A Special fluorine-containing pressure-sensitive adhesive and preparation method thereof 四川轻化工大学 2021-05-11 CN claimed
US-10584278-B2 Proppant having amphiphobic coatings and methods for making and using same CARBO CERAMICS INC. (US) 2020-03-10 US claimed
US-20190225878-A1 PROPPANT HAVING AMPHIPHOBIC COATINGS AND METHODS FOR MAKING AND USING SAME CARBO CERAMICS INC. 2019-07-25 US claimed
US-10246632-B2 Proppant having amphiphobic coatings and methods for making and using same CARBO CERAMICS INC. (US) 2019-04-02 US claimed
US-20170121596-A1 PROPPANT HAVING AMPHIPHOBIC COATINGS AND METHODS FOR MAKING AND USING SAME CARBO CERAMICS, INC. 2017-05-04 US claimed
US-9540493-B2 Surface modification method and surface-modified elastic body SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-01-10 US claimed
US-7538177-B2 Crosslinkable fluorinated aromatic prepolymer and its uses ASAHI GLASS COMPANY, LIMITED (JP) 2009-05-26 US claimed
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF, INC. 2009-04-23 US claimed
US-20080132669-A1 CROSSLINKABLE FLUORINATED AROMATIC PREPOLYMER AND ITS USES ASAHI GLASS COMPANY, LIMITED (JP) 2008-06-05 US claimed
EP-1897897-A1 CROSSLINKABLE FLUORINE-CONTAINING AROMATIC PREPOLYMER AND USE THEREOF Asahi Glass Company, Limited (JP) 2008-03-12 EP claimed
EP-1543074-B1 UV-CURABLE RESIN COMPOSITION FOR CLADDING OPTICAL FIBER SSCP CO LTD (KR) 2008-02-27 EP claimed
US-7046904-B2 UV-curable resin composition for cladding optical fiber SSCP CO., LTD. (KR) 2006-05-16 US claimed
EP-1543074-A4 UV-CURABLE RESIN COMPOSITION FOR CLADDING OPTICAL FIBER SSCP CO LTD (KR) 2006-01-04 EP claimed
EP-1543074-A1 UV-CURABLE RESIN COMPOSITION FOR CLADDING OPTICAL FIBER SSCP Co., Ltd. (KR) 2005-06-22 EP claimed
WO-2004024814-A1 UV-CURABLE RESIN COMPOSITION FOR CLADDING OPTICAL FIBER SSCP CO., LTD. (KR) 2004-03-25 WO claimed
US-6519380-B2 Athermalized integrated optical waveguide devices CORNING INCORPORATED 2003-02-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME TET1, TET2, TET3 TSHR 3749/4885ALDH1A1 457/4885TP53 879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.