SCHEMBL9489155

SCHEMBL9489155

CC(C)C[C@H](N)C(=O)NCC(=O)Nc1ccc2ccccc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.60
RAB9A P51151 2/20 0.60
GAA P10253 1/20 0.60
LARS1 Q9P2J5 1/20 0.57
TERT O14746 5/20 0.54
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
CYP1A2 P05177 2/20 0.52
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP2C19 P33261 1/20 0.52
HIF1A Q16665 1/20 0.52
MAPT P10636 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
POLB P06746 1/20 0.51
LMNA P02545 3/20 0.48
NPC1 O15118 1/20 0.48
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29838822 1.00 SMN1; SMN2 (0.60) SMN1; SMN2RAB9AGAALARS1TERT
SCHEMBL1820784 0.87 LARS1 (0.64) SMN1; SMN2RAB9AGAALARS1MEN1
SCHEMBL21171627 0.87 LARS1 (0.64) SMN1; SMN2RAB9AGAALARS1MEN1
SCHEMBL30533426 0.87 LARS1 (0.64) SMN1; SMN2RAB9AGAALARS1MEN1
Hydrochloric Acid SCHEMBL27496312 0.86 LARS1 (0.63) SMN1; SMN2RAB9AGAALARS1MEN1
Hydrochloric Acid SCHEMBL10600620 0.86 LARS1 (0.63) SMN1; SMN2RAB9AGAALARS1MEN1
Leucine SCHEMBL9400283 0.82 LARS1 (0.59) SMN1; SMN2RAB9AGAALARS1MEN1
SCHEMBL10439613 0.81 LARS1 (0.52) RAB9ALARS1MEN1KMT2AL3MBTL1
SCHEMBL10782294 0.80 LARS1 (0.46) SMN1; SMN2GAALARS1TERTMEN1
SCHEMBL11292757 0.80 ANPEP (0.52) SMN1; SMN2RAB9ATERTKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4874695-A COLORIMETRIC ANALYSIS AMERICAN HOME PRODUCTS CORP. (US) 1989-10-17 US claimed
WO-2023088470-A1 PROBIOTIC COMPOSITIONS FOR TREATMENT OF HAIR LOSS THE CHINESE UNIVERSITY OF HONG KONG (CN) 2023-05-25 WO disclosed
EP-0255341-B1 REAGENT FOR TESTING PERIODONTAL DISEASES SUNSTAR KABUSHIKI KAISHA (JP) 1993-02-03 EP disclosed
US-5137811-A Method for diagnosing periodontal diseases with a substrate specific for aminopeptidase activity of periodontopathic bacteria SUNSTAR KABUSHIKI KAISHA (JP) 1992-08-11 US disclosed
US-4874695-A COLORIMETRIC ANALYSIS AMERICAN HOME PRODUCTS CORP. (US) 1989-10-17 US disclosed
EP-0255341-A2 Reagent for testing periodontal diseases SUNSTAR KABUSHIKI KAISHA (JP) 1988-02-03 EP disclosed