Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | RARB | P10826 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487524 | 0.97 | TSHR (0.59) | TSHRRARBTP53PLA2G4B | |
| SCHEMBL9489047 | 0.96 | RARB (0.59) | TSHRRARBTP53PLA2G4B | |
| SCHEMBL9489319 | 0.96 | RARB (0.59) | TSHRRARBTP53PLA2G4B | |
| SCHEMBL9490197 | 0.96 | RARB (0.59) | TSHRRARBTP53PLA2G4B | |
| SCHEMBL9487959 | 0.96 | RARB (0.59) | TSHRRARBTP53PLA2G4B | |
| SCHEMBL9488732 | 0.96 | TSHR (0.63) | TSHRRARBL3MBTL1TP53PLA2G4B | |
| SCHEMBL9488551 | 0.94 | TSHR (0.60) | TSHRRARBTP53PLA2G4B | |
| SCHEMBL9489406 | 0.93 | RARB (0.60) | TSHRRARBTP53PLA2G4B | |
| SCHEMBL9490043 | 0.93 | RARB (0.60) | TSHRRARBTP53PLA2G4B | |
| SCHEMBL9489257 | 0.93 | RARB (0.60) | TSHRRARBTP53PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236618-A | Liquid crystal phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-17 | — | — | US | disclosed |
| EP-0168043-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1990-11-07 | — | — | EP | disclosed |
| US-4744918-A | Liquid crystal phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-05-17 | — | — | US | disclosed |