SCHEMBL9490282

SCHEMBL9490282

O=[N+]([O-])c1cc(O)c(O)cc1CO

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.74
ALOX15 P16050 3/20 0.62
ALOX12 P18054 2/20 0.62
ALDH1A1 P00352 4/20 0.43
CYP3A4 P08684 1/20 0.43
GPR35 Q9HC97 4/20 0.42
MAPK1 P28482 3/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
CYP1A2 P05177 2/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 1/20 0.42
TTR P02766 1/20 0.42
CYP2C9 P11712 1/20 0.42
RECQL P46063 1/20 0.42
PMP22 Q01453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12682382 0.85 SNCA (1.00) SNCAALOX15ALOX12ALDH1A1CYP3A4
SCHEMBL29678067 0.85 SNCA (0.52) SNCAALOX15ALOX12ALDH1A1CYP3A4
SCHEMBL12776823 0.83 SNCA (0.74) SNCAALOX15ALOX12ALDH1A1CYP3A4
SCHEMBL16022729 0.83 SNCA (0.50) SNCAALOX15ALOX12ALDH1A1GPR35
SCHEMBL1607678 0.82 SNCA (0.51) SNCAALOX15ALOX12ALDH1A1CYP3A4
SCHEMBL13324857 0.81 SNCA (0.50) SNCAALOX15ALOX12ALDH1A1CYP3A4
SCHEMBL13284232 0.81 SNCA (0.50) SNCAALOX15ALOX12ALDH1A1CYP3A4
SCHEMBL3961356 0.79 SNCA (0.49) SNCAALOX15ALOX12ALDH1A1GPR35
SCHEMBL70858 0.79 SNCA (0.67) SNCAALOX15ALOX12ALDH1A1CYP3A4
SCHEMBL1278365 0.79 SNCA (0.67) SNCAALOX15ALOX12ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020220963-A1 AMPHIPHILIC MOLECULE CONTAINING O-NITROBENZYL ESTER-BASED PHOTODEGRADABLE GROUP, AND SYNTHESIS METHOD THEREFOR 大连理工大学 2020-11-05 WO disclosed
EP-3523020-A1 FLEXIBLE AND MULTI-FUNCTIONAL COACERVATES AND HYDROGEL MATERIALS Aarhus Universitet (DK) 2019-08-14 EP disclosed
WO-2018065450-A1 FLEXIBLE AND MULTI-FUNCTIONAL COACERVATES AND HYDROGEL MATERIALS AARHUS UNIVERSITET (DK) 2018-04-12 WO disclosed
WO-2018065450-A1 FLEXIBLE AND MULTI-FUNCTIONAL COACERVATES AND HYDROGEL MATERIALS AARHUS UNIVERSITET (DK) 2018-04-12 WO disclosed
US-9610257-B2 Small molecule xanthine oxidase inhibitors and methods of use BAYLOR COLLEGE OF MEDICINE (US) 2017-04-04 US disclosed
US-7544721-B2 Photosensitive adhesive composition PRODUITS DENTAIRES PIERRE ROLLAND (FR) 2009-06-09 US disclosed
US-7544721-B2 Photosensitive adhesive composition PRODUITS DENTAIRES PIERRE ROLLAND (FR) 2009-06-09 US disclosed
US-5198520-A Photoresists KABUSHIKI KAISHA TOSHIBA (JP) 1993-03-30 US disclosed
EP-0493367-A2 Silicone resist materials containing polysilanes and methods of making the same KABUSHIKI KAISHA TOSHIBA (JP) 1992-07-01 EP disclosed
US-5017453-A Integrated circuits KABUSHIKI KAISHA TOSHIBA (JP) 1991-05-21 US disclosed
US-4822716-A FINE PATTERN SEMICONDUCTOR, INTEGRATED CIRCUIT KABUSHIKI KAISHA TOSHIBA (JP) 1989-04-18 US disclosed
EP-0231497-A1 Silicone resist materials containing polysiloxanes KABUSHIKI KAISHA TOSHIBA (JP) 1987-08-12 EP disclosed