Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490924 | 0.94 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1KMT2AMEN1MAPT | |
| SCHEMBL9489888 | 0.91 | KMT2A (0.46) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9490935 | 0.85 | — | — | |
| SCHEMBL9488905 | 0.84 | KMT2A (0.46) | CYSLTR2CYSLTR1KMT2AALDH1A1 | |
| SCHEMBL9488613 | 0.84 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1MAPT | |
| SCHEMBL9490426 | 0.83 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1 | |
| SCHEMBL9372946 | 0.82 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1 | |
| SCHEMBL9371854 | 0.82 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1KMT2AMEN1 | |
| SCHEMBL9374065 | 0.81 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1 | |
| SCHEMBL9373086 | 0.81 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| CN-1037895-A | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICA INC (US) | 1989-12-13 | — | — | CN | disclosed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |