Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.59 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.59 |
| ▸ | GSR | P00390 | 1/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.50 |
| ▸ | ARG2 | P78540 | 4/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | NOS1 | P29475 | 3/20 | 0.49 |
| ▸ | NOS3 | P29474 | 2/20 | 0.49 |
| ▸ | NOS2 | P35228 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27608915 | 0.98 | GRIK1 (0.61) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL28307137 | 0.98 | GRIK1 (0.61) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL28580679 | 0.98 | GRIK1 (0.61) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL5967305 | 0.92 | GRIK1 (0.68) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL2730539 | 0.92 | GRIK1 (0.68) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL38735 | 0.92 | GRIK1 (0.68) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL23531056 | 0.90 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL262931 | 0.90 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL3696105 | 0.90 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL5478969 | 0.90 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249169-B1 | PEPTIDES INFLUENCING DIURESE AND NATRIURESE, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-20 | — | — | EP | claimed |
| US-5011825-A | Treatment of hypertension, diabetes, edema | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | claimed |
| CN-87102304-A | Pharmaceutical preparation containing compounds with antidementia effect and its application in preventing and treating cognitive dysfunction | — | 1987-12-30 | — | — | CN | claimed |
| CN-101611053-B | Anti-angiogenic compounds | COVX TECHNOLOGIES IRELAND LTD | 2015-06-03 | — | — | CN | disclosed |
| CN-101611053-A | Anti-angiogenic compounds | COVX TECHNOLOGIES IRELAND LTD (IE) | 2009-12-23 | — | — | CN | disclosed |
| CN-1260207-C | Basic amino acid derivatives as gelation agents | AJINOMOTO KK (JP) | 2006-06-21 | — | — | CN | disclosed |
| CN-1541998-A | Basic amino acid derivatives as gelation agents | ֮����ʽ���� | 2004-11-03 | — | — | CN | disclosed |
| CN-1031267-C | Compounds for anti-dementia medicine and its usage | HOECHST AG (DE) | 1996-03-13 | — | — | CN | disclosed |
| US-5011825-A | Treatment of hypertension, diabetes, edema | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| CN-87102304-A | Pharmaceutical preparation containing compounds with antidementia effect and its application in preventing and treating cognitive dysfunction | — | 1987-12-30 | — | — | CN | disclosed |