Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4221722 | 0.79 | TSHR (0.50) | TSHRTDP1ALDH1A1 | |
| SCHEMBL309317 | 0.79 | TSHR (0.39) | TSHRTDP1 | |
| SCHEMBL275965 | 0.77 | TSHR (0.40) | TSHRTDP1ALDH1A1 | |
| SCHEMBL1417440 | 0.77 | TSHR (0.40) | TSHRTDP1ALDH1A1 | |
| SCHEMBL31096374 | 0.77 | TSHR (0.40) | TSHRTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21358714 | 0.75 | TSHR (0.36) | TSHRTDP1 | |
| SCHEMBL5014809 | 0.74 | TSHR (0.38) | TSHRTDP1ALDH1A1 | |
| SCHEMBL13476669 | 0.74 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL12328299 | 0.72 | — | — | |
| SCHEMBL11860148 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266758-B1 | PREPARATION OF SILANE AND AMINE ALANES | ETHYL CORPORATION (US) | 1993-01-27 | — | — | EP | disclosed |
| US-4757154-A | Reacting alkali metal aluminum tetrahydride, silicon tetrachloride, complexing tertiary amine | ETHYL CORPORATION (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0266758-A2 | Preparation of silane and amine alanes | ETHYL CORPORATION (US) | 1988-05-11 | — | — | EP | disclosed |