Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491050 | 0.86 | NMUR2 (0.54) | ACEACE2 | |
| SCHEMBL9509731 | 0.83 | ACE (0.66) | ACEACE2TSHR | |
| SCHEMBL9551626 | 0.83 | ACE (0.66) | ACEACE2TSHR | |
| SCHEMBL9489896 | 0.83 | PREP (0.56) | — | |
| SCHEMBL8116561 | 0.80 | DPP4 (0.53) | — | |
| SCHEMBL9509127 | 0.79 | ACE (0.63) | ACEACE2TSHR | |
| SCHEMBL18064456 | 0.78 | HTRA1 (0.55) | ACEACE2TSHR | |
| SCHEMBL16576586 | 0.78 | HTRA1 (0.55) | ACEACE2TSHR | |
| SCHEMBL8017603 | 0.77 | TACR1 (0.54) | TACR1 | |
| SCHEMBL19559815 | 0.76 | HTRA1 (0.51) | ACEACE2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255341-B1 | REAGENT FOR TESTING PERIODONTAL DISEASES | SUNSTAR KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5137811-A | Method for diagnosing periodontal diseases with a substrate specific for aminopeptidase activity of periodontopathic bacteria | SUNSTAR KABUSHIKI KAISHA (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0255341-A2 | Reagent for testing periodontal diseases | SUNSTAR KABUSHIKI KAISHA (JP) | 1988-02-03 | — | — | EP | disclosed |