Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467062 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTCHRM2MEN1KMT2A | |
| SCHEMBL14756184 | 0.81 | CHRM2 (0.63) | SLC2A1SMN1; SMN2CYP1A2MAPTKDM4E | |
| SCHEMBL761211 | 0.81 | CA12 (0.49) | CYP1A2RAB9ACYP2A6 | |
| SCHEMBL2473241 | 0.80 | CHRM2 (0.66) | KDM4ECHRM2CHRM1CHRM3MEN1 | |
| SCHEMBL616311 | 0.80 | CYP1A2 (0.59) | SLC2A1SMN1; SMN2CYP1A2MAPTKDM4E | |
| SCHEMBL9491759 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2CYP1A2MAPTKDM4ENPC1 | |
| SCHEMBL9667596 | 0.78 | CHRM2 (0.67) | SLC2A1SMN1; SMN2CYP1A2MAPTKDM4E | |
| SCHEMBL11746659 | 0.78 | PTGS1 (0.56) | SLC2A1SMN1; SMN2CYP1A2MAPTKDM4E | |
| SCHEMBL15980804 | 0.78 | SMN1; SMN2 (0.51) | SLC2A1SMN1; SMN2CYP1A2MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11280297 | 0.77 | RAD52 (0.56) | SLC2A1SMN1; SMN2CYP1A2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225442-A | Melatoninergic disorders | ADIR ET COMPAGNIE (FR) | 1993-07-06 | — | — | US | disclosed |
| EP-0447285-B1 | NAPHTHALENE DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0447285-A1 | Naphthalene derivatives, procedure for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-09-18 | — | — | EP | disclosed |