Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.62 |
| ▸ | CCND1 | P24385 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386344 | 0.87 | CDK4 (0.60) | CDK4CCND1LMNAHTTALDH1A1 | |
| SCHEMBL8122231 | 0.80 | CYP24A1 (0.62) | CDK4CCND1LMNAHTTALDH1A1 | |
| SCHEMBL31083788 | 0.78 | CDK4 (0.70) | CDK4CCND1LMNAHTTALDH1A1 | |
| SCHEMBL3995842 | 0.78 | CDK4 (0.70) | CDK4CCND1LMNAHTTALDH1A1 | |
| SCHEMBL9358675 | 0.78 | CDK4 (0.63) | CDK4CCND1LMNAHTTALDH1A1 | |
| SCHEMBL5428812 | 0.77 | HTT (0.60) | CDK4CCND1LMNAHTTALDH1A1 | |
| Potassium Ion SCHEMBL11621859 | 0.76 | CDK4 (0.56) | CDK4CCND1LMNAHTTALDH1A1 | |
| SCHEMBL135070 | 0.75 | CDK4 (0.78) | CDK4CCND1LMNAHTTHTR2A | |
| SCHEMBL4863420 | 0.75 | CDK4 (0.78) | CDK4CCND1LMNAHTTHTR2A | |
| SCHEMBL30418240 | 0.75 | CDK4 (0.66) | CDK4CCND1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273993-A | Antiarthritic agents; osteoporosis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-12-28 | — | — | US | disclosed |
| US-5192785-A | Sulfamates as antiglaucoma agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0403185-A2 | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-19 | — | — | EP | disclosed |