Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | LIG1 | P18858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659231 | 0.81 | HPGD (0.66) | HSD17B10HPGDTSHRMAPK1MEN1 | |
| SCHEMBL9722020 | 0.81 | SMN1; SMN2 (0.50) | HPGDMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL9788863 | 0.81 | MEN1 (0.50) | HPGDMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL9722015 | 0.81 | SMN1; SMN2 (0.50) | HPGDMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL566437 | 0.81 | CDK4 (0.61) | HSD17B10HPGDTSHRMAPK1MEN1 | |
| SCHEMBL566438 | 0.81 | CDK4 (0.61) | HSD17B10HPGDTSHRMAPK1MEN1 | |
| SCHEMBL10436451 | 0.79 | MAPT (0.51) | HPGDMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL9625931 | 0.79 | MEN1 (0.49) | HPGDMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL10436448 | 0.79 | MAPT (0.51) | HPGDMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL9626007 | 0.79 | MEN1 (0.49) | HPGDMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229033-B1 | THIOL/ENE COMPOSITIONS | LOCTITE (IRELAND) Ltd. (IE) | 1993-03-03 | — | — | EP | disclosed |
| US-5021512-A | Curable | LOCTITE (IRELAND) LTD. (IE) | 1991-06-04 | — | — | US | disclosed |
| EP-0229033-A2 | Thiol/ene compositions | LOCTITE (IRELAND) Ltd. (IE) | 1987-07-15 | — | — | EP | disclosed |