Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494727 | 1.00 | RARB (0.58) | RARBS1PR1S1PR3PTPN11MEN1 | |
| SCHEMBL17445757 | 0.96 | RARB (0.63) | RARBS1PR1S1PR3PTPN11MEN1 | |
| SCHEMBL10529774 | 0.94 | RARB (0.57) | RARBS1PR1S1PR3PTPN11MEN1 | |
| SCHEMBL10527538 | 0.94 | RARB (0.57) | RARBS1PR1S1PR3PTPN11MEN1 | |
| SCHEMBL9399589 | 0.93 | RARB (0.55) | RARBS1PR1S1PR3PTPN11MEN1 | |
| SCHEMBL15615806 | 0.89 | RARB (0.45) | RARBS1PR1S1PR3PTPN11MEN1 | |
| SCHEMBL15615815 | 0.89 | RARB (0.45) | RARBS1PR1S1PR3PTPN11MEN1 | |
| SCHEMBL9247693 | 0.89 | PTPN11 (0.54) | RARBS1PR1S1PR3PTPN11CYP3A4 | |
| SCHEMBL9244788 | 0.89 | PTPN11 (0.54) | RARBS1PR1S1PR3PTPN11CYP3A4 | |
| SCHEMBL9513744 | 0.88 | RARB (0.60) | RARBS1PR1S1PR3PTPN11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273680-A | A chiral tilted smectic liquid crystal based on terphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0329752-B1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0329752-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1989-08-30 | — | — | EP | disclosed |
| WO-1989002425-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-03-23 | — | — | WO | disclosed |