Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485851 | 1.00 | TSHR (0.45) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL9493156 | 1.00 | TSHR (0.45) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL9485756 | 1.00 | TSHR (0.45) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL9486565 | 0.98 | PRSS1 (0.46) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL9486927 | 0.98 | PRSS1 (0.46) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL9486324 | 0.97 | TSHR (0.43) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL9486420 | 0.95 | PRSS1 (0.43) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL9487338 | 0.94 | CYP3A4 (0.54) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL9487064 | 0.94 | CYP3A4 (0.54) | TSHRCYP3A4ATMTDP1PRSS1 | |
| SCHEMBL9486603 | 0.94 | CYP3A4 (0.54) | TSHRCYP3A4ATMTDP1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260051-A | Surfactants, soaps, toothpastes | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0493927-A1 | Phosphate esters and compositions containing them | UNILEVER PLC (GB) | 1992-07-08 | — | — | EP | disclosed |