Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.56 |
| ▸ | RARA | P10276 | 2/20 | 0.56 |
| ▸ | RARG | P13631 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14453078 | 0.92 | RARB (0.48) | RARBRARARARGHSD17B10HTR2A | |
| SCHEMBL17108449 | 0.89 | RARB (0.43) | RARBRARARARGHTR2ATSHR | |
| SCHEMBL13632415 | 0.87 | NPC1 (0.44) | RARBRARARARGHSD17B10ALDH1A1 | |
| SCHEMBL17108392 | 0.86 | RARB (0.41) | RARBRARARARGHSD17B10HTR2A | |
| SCHEMBL16521127 | 0.85 | RARB (0.56) | RARBRARARARGHSD17B10HTR2A | |
| SCHEMBL18416778 | 0.85 | RARB (0.56) | RARBRARARARGHSD17B10HTR2A | |
| SCHEMBL16258122 | 0.85 | RARB (0.56) | RARBRARARARGHSD17B10HTR2A | |
| SCHEMBL16258054 | 0.85 | RARB (0.56) | RARBRARARARGHSD17B10HTR2A | |
| SCHEMBL12966415 | 0.84 | RARB (0.55) | RARBRARARARGHSD17B10HTR2A | |
| SCHEMBL24401721 | 0.83 | RARB (0.47) | RARBRARARARGHSD17B10HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273680-A | A chiral tilted smectic liquid crystal based on terphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0329752-B1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0329752-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1989-08-30 | — | — | EP | disclosed |
| WO-1989002425-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-03-23 | — | — | WO | disclosed |