Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494766 | 1.00 | GAA (0.44) | GAAHPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL9764435 | 0.89 | BAZ2B (0.39) | GAAHPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL9764431 | 0.89 | BAZ2B (0.39) | GAAHPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL9242901 | 0.86 | HPGD (0.32) | GAAHPGDPOLB | |
| SCHEMBL9242904 | 0.86 | HPGD (0.32) | GAAHPGDPOLB | |
| SCHEMBL9494943 | 0.82 | HPGD (0.39) | HPGDSMN1; SMN2MAPTPOLB | |
| SCHEMBL9679868 | 0.82 | HPGD (0.39) | HPGDSMN1; SMN2MAPTPOLB | |
| SCHEMBL9496185 | 0.81 | — | — | |
| SCHEMBL9496193 | 0.81 | — | — | |
| SCHEMBL9492392 | 0.81 | HPGD (0.32) | HPGDSMN1; SMN2LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457714-A1 | Thiadiazabicyclononane derivatives, process for their preparation, intermediates and their use as herbicides | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | claimed |
| US-5229514-A | Thiourea compounds containing pyridazine ring | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |
| US-5135562-A | 8-thia-1,6-diazabicyclo[4.3.0]nonane herbicides | CIBA-GEIGY CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0457714-A1 | Thiadiazabicyclononane derivatives, process for their preparation, intermediates and their use as herbicides | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |