Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 6/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495021 | 1.00 | FFAR1 (0.48) | FFAR1TSHRHSD17B10FFAR4RARB | |
| SCHEMBL9494848 | 0.96 | HSD17B10 (0.50) | FFAR1TSHRHSD17B10FFAR4RARB | |
| SCHEMBL9494844 | 0.96 | HSD17B10 (0.50) | FFAR1TSHRHSD17B10FFAR4RARB | |
| SCHEMBL10512096 | 0.95 | FFAR1 (0.44) | FFAR1TSHRHSD17B10FFAR4RARB | |
| SCHEMBL9495977 | 0.95 | HSD17B10 (0.52) | FFAR1TSHRHSD17B10FFAR4RARB | |
| SCHEMBL9495969 | 0.95 | HSD17B10 (0.52) | FFAR1TSHRHSD17B10FFAR4RARB | |
| SCHEMBL9500345 | 0.95 | HSD17B10 (0.52) | FFAR1TSHRHSD17B10FFAR4RARB | |
| SCHEMBL9500354 | 0.95 | HSD17B10 (0.52) | FFAR1TSHRHSD17B10FFAR4RARB | |
| SCHEMBL9495576 | 0.92 | FFAR1 (0.48) | FFAR1TSHRHSD17B10FFAR4ACACB | |
| SCHEMBL9495588 | 0.92 | FFAR1 (0.48) | FFAR1TSHRHSD17B10FFAR4ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |