Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414855 | 0.80 | ESR1 (0.52) | ESR1ESR2PDCD1CD274TDP1 | |
| SCHEMBL5147307 | 0.77 | ESR1 (0.45) | ESR1ESR2PDCD1CD274TDP1 | |
| SCHEMBL278254 | 0.75 | ESR1 (0.58) | ESR1ESR2PDCD1CD274TDP1 | |
| SCHEMBL28445716 | 0.74 | ESR1 (0.46) | ESR1ESR2PDCD1CD274TDP1 | |
| SCHEMBL14124071 | 0.74 | ESR1 (0.50) | ESR1ESR2PDCD1CD274TDP1 | |
| SCHEMBL9500946 | 0.73 | TAAR1 (0.39) | ESR1ESR2PDCD1CD274TDP1 | |
| SCHEMBL28311929 | 0.73 | TAAR1 (0.46) | ESR1ESR2PDCD1CD274TDP1 | |
| SCHEMBL71466 | 0.69 | ESR1 (0.62) | ESR1ESR2PDCD1CD274TDP1 | |
| SCHEMBL27504862 | 0.69 | ESR1 (0.50) | ESR1ESR2PDCD1CD274TDP1 | |
| SCHEMBL108324 | 0.69 | ESR1 (0.54) | ESR1ESR2PDCD1CD274TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533202-A1 | Use of capped surfactants for production of rigid polyurethane foams blown with hydrochlorofluorocarbons | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| US-4468339-A | AND SOLUBILIZER WHICH IS REACTION OF CARBOXYLIC ACID ACYLATING AGENT WITH HYDROCARBON SUBSTITMENT AND HYDROXYAMINE | THE LUBRIZOL CORPORATION (US) | 1984-08-28 | — | — | US | disclosed |
| US-4432865-A | REACTING WITH MINERAL ACID OR POLYHYDROXY COMPOUND, THEN SEPARATION | NORMAN GEORGE R | 1984-02-21 | — | — | US | disclosed |
| US-4431524-A | DEMETALLIZATION BY ADDING A MINERAL ACID AND POLYHYDROXY COMPOUND SUCH AS CELLULOSE FIBERS | NORMAN GEORGE R | 1984-02-14 | — | — | US | disclosed |
| EP-0084966-A2 | Aqueous compositions containing overbased materials | The Lubrizol Corporation (US) | 1983-08-03 | — | — | EP | disclosed |
| US-4382128-A | Polyolefin grafted with polycarboxylic acid, ester or anhydride and modified with polyhydroxy compound | STANDARD OIL COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| US-4258137-A | INCORPORATING AN EPOXY RESIN AND CURING AGENT TO ATTAIN RIGIDITY | W. R. GRACE & CO. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4250005-A | Radiation cross-linked polyurethane foams | SCOTT PAPER COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4144027-A | SHRINKPROOFING KERATIN-CONTAINING FABRICS BY REACTION WITH A POLYETHER POLYOL AND A DIISOCYANATE | MILLIKEN RESEARCH CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4046744-A | Thermosetting coatings based on ketoxime-blocked isocyanates and oxazolidines | ROHM AND HAAS COMPANY (US) | 1977-09-06 | — | — | US | disclosed |