SCHEMBL9495178

SCHEMBL9495178

C=CC(C)=O.CC1C(C=O)CC2CC1C2(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
CYP19A1 P11511 10/20 0.34
CYP17A1 P05093 5/20 0.34
ALDH1A1 P00352 1/20 0.34
EPHX2 P34913 1/20 0.34
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2852181 0.87 TDP1 (0.36) SCN1ASCN2ASCN3ATDP1CYP19A1
SCHEMBL9187247 0.87 TDP1 (0.36) SCN1ASCN2ASCN3ATDP1CYP19A1
SCHEMBL9184208 0.87 TDP1 (0.36) SCN1ASCN2ASCN3ATDP1CYP19A1
SCHEMBL18492254 0.76 TDP1 (0.40) SCN1ASCN2ASCN3ATDP1CYP19A1
SCHEMBL10882916 0.76 TDP1 (0.40) SCN1ASCN2ASCN3ATDP1CYP19A1
SCHEMBL18492257 0.76 TDP1 (0.40) SCN1ASCN2ASCN3ATDP1CYP19A1
SCHEMBL18492256 0.76 TDP1 (0.40) SCN1ASCN2ASCN3ATDP1CYP19A1
SCHEMBL9614687 0.74 TDP1 (0.35) SCN1ASCN2ASCN3ATDP1CYP19A1
SCHEMBL9614689 0.74 TDP1 (0.35) SCN1ASCN2ASCN3ATDP1CYP19A1
SCHEMBL17213197 0.72 CYP19A1 (0.49) SCN1ASCN2ASCN3ATDP1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0382934-B1 TRICYCLIC KETONES, METHOD OF MAKING THEM AND THEIR APPLICATION AS PERFUME AGENTS FIRMENICH SA (CH) 1993-04-28 EP claimed