Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 10/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500577 | 1.00 | LSS (0.41) | LSSGAAMAPTFFAR1PLG | |
| SCHEMBL9500584 | 1.00 | LSS (0.41) | LSSGAAMAPTFFAR1PLG | |
| SCHEMBL9495192 | 1.00 | LSS (0.41) | LSSGAAMAPTFFAR1PLG | |
| SCHEMBL9496416 | 0.99 | LSS (0.39) | LSSGAAMAPTFFAR1BACE1 | |
| SCHEMBL9496412 | 0.99 | LSS (0.39) | LSSGAAMAPTFFAR1BACE1 | |
| SCHEMBL9495466 | 0.96 | LSS (0.39) | LSSGAAMAPTFFAR1PLG | |
| SCHEMBL9497486 | 0.96 | LSS (0.39) | LSSGAAMAPTFFAR1PLG | |
| SCHEMBL10513699 | 0.96 | LSS (0.39) | LSSGAAMAPTFFAR1PLG | |
| SCHEMBL9497473 | 0.96 | LSS (0.39) | LSSGAAMAPTFFAR1PLG | |
| SCHEMBL9497090 | 0.96 | LSS (0.39) | LSSGAAMAPTFFAR1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |