Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714538 | 0.87 | POLB (0.63) | ABCB1CYP3A4CYP2C9MEN1KMT2A | |
| SCHEMBL9714257 | 0.86 | CYP3A4 (0.60) | ABCB1CYP3A4CYP2C9LMNACYP1A2 | |
| SCHEMBL9714318 | 0.85 | POLB (0.56) | ABCB1CYP3A4CYP2C9LMNACYP1A2 | |
| SCHEMBL9241810 | 0.84 | POLB (0.71) | ABCB1CYP3A4CYP2C9LMNACYP1A2 | |
| SCHEMBL9714239 | 0.84 | ABCB1 (0.56) | ABCB1CYP3A4CYP2C9LMNACYP1A2 | |
| SCHEMBL8166763 | 0.83 | POLB (0.74) | ABCB1CYP3A4CYP2C9MEN1KMT2A | |
| SCHEMBL9652010 | 0.83 | POLB (0.74) | ABCB1CYP3A4CYP2C9MEN1KMT2A | |
| SCHEMBL10752824 | 0.82 | ABCB1 (0.68) | ABCB1 | |
| SCHEMBL9714400 | 0.82 | ABCB1 (0.64) | ABCB1 | |
| SCHEMBL9824817 | 0.81 | ABCB1 (0.58) | ABCB1CYP3A4CYP2C9LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5237099-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2-alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1993-08-17 | — | — | US | disclosed |
| US-4814349-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2 alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1989-03-21 | — | — | US | disclosed |