Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495558 | 1.00 | FFAR1 (0.37) | FFAR1P2RY6FFAR4ALDH1A1LMNA | |
| SCHEMBL10509152 | 0.96 | FFAR1 (0.35) | FFAR1P2RY6FFAR4ALDH1A1LMNA | |
| SCHEMBL9496088 | 0.92 | FFAR1 (0.35) | FFAR1P2RY6FFAR4LMNABACE1 | |
| SCHEMBL9496097 | 0.92 | FFAR1 (0.35) | FFAR1P2RY6FFAR4LMNABACE1 | |
| SCHEMBL9497431 | 0.91 | FFAR1 (0.35) | FFAR1P2RY6FFAR4MAPTBACE1 | |
| SCHEMBL9497441 | 0.91 | FFAR1 (0.35) | FFAR1P2RY6FFAR4MAPTBACE1 | |
| SCHEMBL9495003 | 0.90 | FFAR1 (0.38) | FFAR1P2RY6FFAR4BACE1ACACB | |
| SCHEMBL9494993 | 0.90 | FFAR1 (0.38) | FFAR1P2RY6FFAR4BACE1ACACB | |
| SCHEMBL9496293 | 0.90 | FFAR1 (0.34) | FFAR1P2RY6FFAR4MAPT | |
| SCHEMBL9498673 | 0.90 | FFAR1 (0.34) | FFAR1P2RY6FFAR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |