Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006398 | 1.00 | MAPT (0.59) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL95367 | 1.00 | MAPT (0.59) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL999365 | 1.00 | MAPT (0.59) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL1006411 | 1.00 | MAPT (0.59) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL1006936 | 1.00 | MAPT (0.59) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL1006131 | 1.00 | MAPT (0.59) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL1006371 | 1.00 | MAPT (0.59) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL1006478 | 1.00 | MAPT (0.59) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL999810 | 1.00 | MAPT (0.59) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL1008972 | 1.00 | MAPT (0.59) | MAPTRXFP1SIGMAR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526832-B | Method for preparing polysubstituted alicyclic compound | 浙江师范大学 | 2022-06-10 | — | — | CN | claimed |
| CN-107963982-B | Polyisocyanate composition and isocyanate polymer composition | 旭化成株式会社 | 2021-11-12 | — | — | CN | claimed |
| EP-2612656-B1 | PROCESS FOR PRODUCING DRUG BLOCK-COPOLYMER COMPOSITE AND PHARMACEUTICAL PRODUCT CONTAINING SAME | NIPPON KAYAKU KK (JP) | 2020-02-26 | — | — | EP | claimed |
| CN-110526832-A | A method of preparing polysubstituted alicyclic compound | UNIV ZHEJIANG NORMAL | 2019-12-03 | — | — | CN | claimed |
| CN-106176721-A | The cancer prevention of organic selenium compounds and therapeutic use | 深圳福山生物科技有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-106146372-A | For preventing and treat the organic selenium compounds of cancer | 深圳福山生物科技有限公司 | 2016-11-23 | — | — | CN | claimed |
| EP-1661892-B1 | CONDENSED RING COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO (JP) | 2013-07-24 | — | — | EP | claimed |
| CN-103130705-A | Benzo five-membered unsaturated heterocyclic compound or pharmaceutically acceptable salt thereof, and preparation method, pharmaceutical composition and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-06-05 | — | — | CN | claimed |
| US-20120226036-A1 | SUBSTITUTED CARBONYL COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2012-09-06 | — | — | US | claimed |
| EP-2481732-A1 | Condensed ring compound and use thereof | Ono Pharmaceutical Co., Ltd. (JP) | 2012-08-01 | — | — | EP | claimed |
| EP-1606019-A1 | CANNABINOID RECEPTOR INVERSE AGONISTS AND NEUTRAL ANTAGONISTS AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE DISORDERS | The University Court of The University of Aberdeen (GB) | 2005-12-21 | — | — | EP | claimed |
| US-20050215526-A1 | Melanin concentrating hormone receptor antagonist | AMGEN, INC. | 2005-09-29 | — | — | US | claimed |
| WO-2005019167-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST | AMGEN, INC. (US) | 2005-03-03 | — | — | WO | claimed |
| WO-2004078261-A1 | CANNABINOID RECEPTOR INVERSE AGONISTS AND NEUTRAL ANTAGONISTS AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE DISORDERS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2004-09-16 | — | — | WO | claimed |
| US-6245774-B1 | ANTIINFLAMMATORY AGENTS; BRONCHODILATOR AGENTS | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-06-12 | — | — | US | claimed |
| EP-0758320-A1 | TRYPTAMINE DERIVATIVES AS 5-HT-1D RECEPTOR LIGANDS | Allelix Biopharmaceuticals Inc. (CA) | 1997-02-19 | — | — | EP | claimed |
| US-5504101-A | TRYPTAMINE ANALOGS | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1996-04-02 | — | — | US | claimed |
| WO-1995030655-A1 | TRYPTAMINE DERIVATIVES AS 5-HT-1D RECEPTOR LIGANDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1995-11-16 | — | — | WO | claimed |
| CN-1086805-A | (mixing) aryl compound that replaces, its preparation method, its preparation and purposes | HOECHST AG (DE) | 1994-05-18 | — | — | CN | claimed |
| CN-1039023-A | The HMG CoA reductase of 5-oxidation is torn preparation open | MERCK & CO INC (US) | 1990-01-24 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120226036-A1 | SUBSTITUTED CARBONYL COMPOUND | PTGER2, PTGER1, LTB4R2 | MAPT 4683/4885RXFP1 317/4885SIGMAR1 494/4885 |
| US-20050215526-A1 | Melanin concentrating hormone receptor antagonist | MCHR1, MC1R, NPY1R | MAPT 321/4885RXFP1 28/4885SIGMAR1 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.