Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495948 | 1.00 | HRH3 (0.40) | HRH3TSHRHSD17B10KIF11FFAR1 | |
| SCHEMBL10513390 | 0.96 | HRH3 (0.38) | HRH3TSHRHSD17B10KIF11FFAR1 | |
| SCHEMBL9498022 | 0.92 | TSHR (0.44) | HRH3TSHRHSD17B10KIF11FFAR1 | |
| SCHEMBL9498026 | 0.92 | TSHR (0.44) | HRH3TSHRHSD17B10KIF11FFAR1 | |
| SCHEMBL9499565 | 0.91 | FFAR1 (0.38) | HRH3FFAR1 | |
| SCHEMBL9855252 | 0.91 | FFAR1 (0.38) | HRH3FFAR1 | |
| SCHEMBL9499571 | 0.91 | FFAR1 (0.38) | HRH3FFAR1 | |
| SCHEMBL9497569 | 0.91 | TSHR (0.47) | HRH3TSHRHSD17B10KIF11FFAR1 | |
| SCHEMBL9497566 | 0.91 | TSHR (0.47) | HRH3TSHRHSD17B10KIF11FFAR1 | |
| SCHEMBL9495306 | 0.89 | TSHR (0.49) | HRH3TSHRHSD17B10KIF11FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |