⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071187 | 1.00 | — | — | |
| SCHEMBL9275526 | 1.00 | — | — | |
| Methane SCHEMBL27607362 | 0.98 | — | — | |
| SCHEMBL15705535 | 0.86 | — | — | |
| SCHEMBL15705536 | 0.78 | — | — | |
| SCHEMBL9717397 | 0.74 | CYP1A2 (0.33) | — | |
| SCHEMBL3277293 | 0.74 | — | — | |
| SCHEMBL574767 | 0.74 | — | — | |
| SCHEMBL52211 | 0.74 | — | — | |
| SCHEMBL21761546 | 0.72 | ATM (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574473-A | Photovoltaic back adhesive and preparation method thereof | 广州富思德化工科技有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-112812724-B | Polyester adhesive and preparation method thereof | 苏州赛伍应用技术股份有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-112812724-A | Polyester adhesive and preparation method thereof | 苏州赛伍应用技术股份有限公司 | 2021-05-18 | — | — | CN | claimed |
| EP-3478848-A2 | METHODS AND MICROORGANISMS FOR PRODUCING FLAVORS AND FRAGRANCE CHEMICALS | Ardra Bio Inc. (US) | 2019-05-08 | — | — | EP | claimed |
| WO-2018005806-A2 | METHODS AND MICROORGANISMS FOR PRODUCING FLAVORS AND FRAGRANCE CHEMICALS | ARDRA BIO INC. (US) | 2018-01-04 | — | — | WO | claimed |
| JP-4786551-B2 | — | — | 2011-10-05 | — | — | JP | claimed |
| US-7507866-B2 | Decarboxylation/hydroxylation without the release of carbon monoxide by using a mixed-oxide, supported, hydrogenation catalyst based on rhenium oxide with an absense of ruthenium and, in some cases, platinum and palladium; autoclaving malic acid to obtain hydroxybutyrolactone and 1,2,4-butanetriol | BASF AG (DE) | 2009-03-24 | — | — | US | claimed |
| EP-1716091-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS OR CARBOXYLIC ACIDS | BASF SE (DE) | 2009-02-18 | — | — | EP | claimed |
| US-7439046-B2 | Making 4-hydroxy-tetrahydropyran-2-one by converting 2,4-dideoxyhexose or 2,4,6-trideoxyhexose into 4-hydroxy-tetrahydropyran-2-one; 2,4-dideoxyhexose or a 2,4,6-trideoxyhexose prepared from carbonyl compound and acetaldehyde in aldolase and water presence; acetalization, decyclization, cyclization | DSM IP ASSETS B.V. (NL) | 2008-10-21 | — | — | US | claimed |
| US-20070135648-A1 | Decarboxylation/hydroxylation without the release of carbon monoxide by using a mixed-oxide, supported, hydrogenation catalyst based on rhenium oxide with an absense of ruthenium and, in some cases, platinum and palladium; autoclaving malic acid to obtain hydroxybutyrolactone and 1,2,4-butanetriol | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-14 | — | — | US | claimed |
| EP-0418648-B1 | 4-Hydroxytetrahydropyran-2-ones as well as the corresponding dehydroxy carbon acid derivatives, salts and esters, process for their preparation, pharmaceutical preparations as well as precursors | HOECHST AG (DE) | 1995-01-11 | — | — | EP | claimed |
| US-5294724-A | Anticholesterol agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | claimed |
| EP-0578016-A2 | Enzymatic process for the resolution of a racemic mixture of delta-valerolactones | Chemie Linz GmbH (AT) | 1994-01-12 | — | — | EP | claimed |
| US-5266707-A | Anticholesterol | FUJIREBIO INC. (JP) | 1993-11-30 | — | — | US | claimed |
| US-5149834-A | Anticholesterol agent and enzyme inhibitors, for curing arteriosclerosis | FUJIREBIO INC. (JP) | 1992-09-22 | — | — | US | claimed |
| EP-0445827-A2 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO INC. (JP) | 1991-09-11 | — | — | EP | claimed |
| EP-0418648-A1 | 4-Hydroxytetrahydropyran-2-ones as well as the corresponding dehydroxy carbon acid derivatives, salts and esters, process for their preparation, pharmaceutical preparations as well as precursors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-27 | — | — | EP | claimed |
| EP-0306264-A2 | Novel HMG-COA reductase inhibitors | MERCK & CO. INC. (US) | 1989-03-08 | — | — | EP | claimed |
| EP-0010299-B1 | PHARMACEUTICAL COMPOSITION USEFUL FOR THE TREATMENT OF HYPERCHOLESTEREMIA | MERCK & CO. INC. (US) | 1984-02-15 | — | — | EP | claimed |
| EP-0010299-A1 | Pharmaceutical composition useful for the treatment of hypercholesteremia | MERCK & CO. INC. (US) | 1980-04-30 | — | — | EP | claimed |