Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497091 | 1.00 | HSD17B10 (0.49) | HSD17B10TSHRALDH1A1MAPTRAB9A | |
| SCHEMBL9498060 | 1.00 | HSD17B10 (0.49) | HSD17B10TSHRALDH1A1MAPTRAB9A | |
| SCHEMBL9495414 | 1.00 | HSD17B10 (0.49) | HSD17B10TSHRALDH1A1MAPTRAB9A | |
| SCHEMBL9495374 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRALDH1A1MAPTRAB9A | |
| SCHEMBL9497425 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRALDH1A1MAPTRAB9A | |
| SCHEMBL9498393 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRALDH1A1MAPTRAB9A | |
| SCHEMBL9496294 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRALDH1A1MAPTRAB9A | |
| SCHEMBL9496270 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRALDH1A1MAPTRAB9A | |
| SCHEMBL9495936 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRALDH1A1MAPTRAB9A | |
| SCHEMBL9497476 | 0.98 | HSD17B10 (0.46) | HSD17B10TSHRALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |