Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496051 | 1.00 | ACACB (0.49) | ACACBFFAR1FFAR4HSD17B10TSHR | |
| SCHEMBL9495008 | 1.00 | ACACB (0.49) | ACACBFFAR1FFAR4HSD17B10TSHR | |
| SCHEMBL9497071 | 1.00 | ACACB (0.49) | ACACBFFAR1FFAR4HSD17B10TSHR | |
| SCHEMBL9496289 | 1.00 | ACACB (0.49) | ACACBFFAR1FFAR4HSD17B10TSHR | |
| SCHEMBL9499653 | 1.00 | ACACB (0.49) | ACACBFFAR1FFAR4HSD17B10TSHR | |
| SCHEMBL9497511 | 1.00 | ACACB (0.49) | ACACBFFAR1FFAR4HSD17B10TSHR | |
| SCHEMBL9496100 | 1.00 | ACACB (0.49) | ACACBFFAR1FFAR4HSD17B10TSHR | |
| SCHEMBL9498005 | 1.00 | ACACB (0.49) | ACACBFFAR1FFAR4HSD17B10TSHR | |
| SCHEMBL9497929 | 1.00 | ACACB (0.49) | ACACBFFAR1FFAR4HSD17B10TSHR | |
| SCHEMBL9499901 | 1.00 | ACACB (0.49) | ACACBFFAR1FFAR4HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |