Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.89 |
| ▸ | THRB | P10828 | 1/20 | 0.89 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octane SCHEMBL8177774 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Heptane SCHEMBL8360976 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Heptane SCHEMBL8416675 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Hexadecane SCHEMBL15324162 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Heptane SCHEMBL4756107 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Decane SCHEMBL15324160 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Pentadecane SCHEMBL11518215 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Decane SCHEMBL9468904 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Octane SCHEMBL845402 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Heptane SCHEMBL5681355 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347305-B1 | [(Aryl-4-piperazinyl-1)-2-ethoxy]-3 p cymene, the ortho-, meta-, para-monosubstituted or disubstituted phenyl ring derivatives, process for their preparation and medicaments containing the same as the active principle | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) Société à responsabilité limitée dite: (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0445116-A1 | [(ARYL-4-PIPERAZINYL-1)-2 ETHOXY]-3 P-CYMENE, THE ORTHO, META AND PARA DERIVATIVES MONO- OR DISUBSTITUTED ON THE PHENYL NUCLEUS OF SAID PRODUCT, PROCESS FOR PREPARING SAID DERIVATIVES, AND DRUGS CONTAINING SAID COMPOUNDS AS ACTIVE INGREDIENTS | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (IRCEBA) (FR) | 1991-09-11 | — | — | EP | disclosed |
| WO-1989012634-A1 | [(ARYL-4-PIPERAZINYL-1)-2 ETHOXY]-3 P-CYMENE, THE ORTHO, META AND PARA DERIVATIVES MONO- OR DISUBSTITUTED ON THE PHENYL NUCLEUS OF SAID PRODUCT, PROCESS FOR PREPARING SAID DERIVATIVES, AND DRUGS CONTAINING SAID COMPOUNDS AS ACTIVE INGREDIENTS | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES AP (FR) | 1989-12-28 | — | — | WO | disclosed |
| EP-0347305-A1 | [(Aryl-4-piperazinyl-1)-2-ethoxy]-3 p cymene, the ortho-, meta-, para-monosubstituted or disubstituted phenyl ring derivatives, process for their preparation and medicaments containing the same as the active principle | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) Société à responsabilité limitée dite: (FR) | 1989-12-20 | — | — | EP | disclosed |