Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4993413 | 0.93 | TSHR (0.50) | TSHRTHRBALDH1A1LMNAKDM4E | |
| SCHEMBL29009582 | 0.93 | TSHR (0.57) | TSHRTHRBALDH1A1LMNAKDM4E | |
| SCHEMBL8764057 | 0.90 | TSHR (0.50) | TSHRTHRBALDH1A1LMNAKDM4E | |
| SCHEMBL13225853 | 0.89 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL3972903 | 0.88 | TSHR (0.49) | TSHRTHRBALDH1A1LMNAKDM4E | |
| SCHEMBL1254411 | 0.88 | TSHR (0.52) | TSHRTHRBALDH1A1LMNAKDM4E | |
| SCHEMBL14932631 | 0.88 | TSHR (0.45) | TSHRTHRBALDH1A1LMNAKDM4E | |
| SCHEMBL16407302 | 0.87 | TSHR (0.47) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL8432931 | 0.87 | TSHR (0.47) | TSHRTHRBALDH1A1LMNAKDM4E | |
| Bromide SCHEMBL1252822 | 0.86 | TSHR (0.50) | TSHRTHRBALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287818-B1 | POLYMERISABLE COMPOUNDS AND MIXTURE CONTAINING THEM POLYMERISABLE BY RADIATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-26 | — | — | EP | disclosed |
| EP-0287818-A2 | Polymerisable compounds and mixture containing them polymerisable by radiation | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-26 | — | — | EP | disclosed |