Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498228 | 1.00 | GRM2 (0.40) | GRM2FFAR1MAPTGAAMEN1 | |
| SCHEMBL9497773 | 1.00 | GRM2 (0.40) | GRM2FFAR1MAPTGAAMEN1 | |
| SCHEMBL9498353 | 1.00 | GRM2 (0.40) | GRM2FFAR1MAPTGAAMEN1 | |
| SCHEMBL9495359 | 1.00 | GRM2 (0.40) | GRM2FFAR1MAPTGAAMEN1 | |
| SCHEMBL9495350 | 1.00 | GRM2 (0.40) | GRM2FFAR1MAPTGAAMEN1 | |
| SCHEMBL9494914 | 1.00 | GRM2 (0.40) | GRM2FFAR1MAPTGAAMEN1 | |
| SCHEMBL9494906 | 1.00 | GRM2 (0.40) | GRM2FFAR1MAPTGAAMEN1 | |
| SCHEMBL9498218 | 1.00 | GRM2 (0.40) | GRM2FFAR1MAPTGAAMEN1 | |
| SCHEMBL9497783 | 1.00 | GRM2 (0.40) | GRM2FFAR1MAPTGAAMEN1 | |
| SCHEMBL9494952 | 0.99 | GRM2 (0.38) | GRM2FFAR1MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |