Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165400 | 1.00 | HTR2C (0.39) | HTR2CSLC6A4HTR2AHRH1 | |
| SCHEMBL24263583 | 0.84 | CA1 (0.38) | HTR2C | |
| SCHEMBL24784855 | 0.82 | — | — | |
| SCHEMBL26573798 | 0.82 | HTR2C (0.31) | HTR2C | |
| SCHEMBL21067464 | 0.80 | — | — | |
| SCHEMBL10831129 | 0.79 | — | — | |
| SCHEMBL12161918 | 0.78 | — | — | |
| SCHEMBL14471663 | 0.78 | HTR2C (0.32) | HTR2CSLC6A4 | |
| SCHEMBL15888989 | 0.78 | HTR2C (0.32) | HTR2C | |
| SCHEMBL16257913 | 0.78 | CA1 (0.33) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324154-B1 | 1,2 BIS(AMINOMETHYL)CYCLOBUTANE-PLATINUM-COMPLEXES | ASTA Medica Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| US-5023335-A | Antitumor agents | ASTA PHARMA AKTIENGESELLSCHAFT | 1991-06-11 | — | — | US | disclosed |