Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810777 | 1.00 | TSHR (0.63) | TSHRNAAACA12CA1CA2 | |
| SCHEMBL8978821 | 1.00 | TSHR (0.63) | TSHRNAAACA12CA1CA2 | |
| SCHEMBL27719654 | 1.00 | TSHR (0.63) | TSHRNAAACA12CA1CA2 | |
| SCHEMBL3896665 | 1.00 | TSHR (0.63) | TSHRNAAACA12CA1CA2 | |
| SCHEMBL11798288 | 1.00 | TSHR (0.63) | TSHRNAAACA12CA1CA2 | |
| SCHEMBL27917694 | 1.00 | TSHR (0.63) | TSHRNAAACA12CA1CA2 | |
| SCHEMBL17780661 | 1.00 | TSHR (0.63) | TSHRNAAACA12CA1CA2 | |
| SCHEMBL1819190 | 0.98 | TSHR (0.61) | TSHRNAAACA12CA1CA2 | |
| SCHEMBL9497231 | 0.97 | — | — | |
| SCHEMBL891903 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300099-A | Ketal derivatives of drugs, preparation method thereof, pharmaceutical compositions and uses | 南开大学 | 2021-02-02 | — | — | CN | disclosed |
| CN-102559207-B | Liquid crystal aligning agent, polymer, method for producing polymer, liquid crystal alignment film and liquid crystal display device | JSR CORP | 2015-01-14 | — | — | CN | disclosed |
| US-8641816-B2 | Vinyl ether compounds and methods of their preparation and use | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-02-04 | — | — | US | disclosed |
| CN-102559207-A | Liquid crystal aligning agent, polymer, method for producing polymer, liquid crystal alignment film and liquid crystal display device | JSR CORP | 2012-07-11 | — | — | CN | disclosed |
| US-20110105507-A1 | VINYL ETHER COMPOUNDS AND METHODS OF THEIR PREPARATION AND USE | DOW GLOBAL TECHNOLOGIES LLC | 2011-05-05 | — | — | US | disclosed |
| US-7250267-B2 | Cross-reactive sensors | TRUSTEES OF TUFTS COLLEGE (US) | 2007-07-31 | — | — | US | disclosed |
| US-20070122861-A1 | CROSS-REACTIVE SENSORS | TRUSTEES OF TUFTS COLLEGE | 2007-05-31 | — | — | US | disclosed |
| EP-0272110-B1 | ERYTHROMYCIN A DERIVATIVES AND METHOD FOR THE PREPARATION OF THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-4990602-A | Bactericides | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105507-A1 | VINYL ETHER COMPOUNDS AND METHODS OF THEIR PREPARATION AND USE | VCL, ETV6, ETV1 | TSHR 2732/4885NAAA 3418/4885CA12 2708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.