Benzophenone

Benzophenone

SCHEMBL9499396

CC(C)(C)c1ccc(C(=O)O)cc1.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 6/20 0.89
RARB P10826 1/20 0.62
RARG P13631 1/20 0.62
TDP1 Q9NUW8 2/20 0.60
EPHX2 P34913 2/20 0.59
NR1H4 Q96RI1 2/20 0.59
NPC1 O15118 1/20 0.57
HSP90AA1 P07900 1/20 0.57
PKM P14618 1/20 0.57
RAB9A P51151 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
FFAR1 O14842 1/20 0.56
SIRT1 Q96EB6 1/20 0.56
MAPT P10636 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
KCNK9 Q9NPC2 1/20 0.54
DAO P14920 1/20 0.54
TSHR P16473 1/20 0.54
NAPRT Q6XQN6 1/20 0.54
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL9155688 0.94 SRD5A2 (0.77) SRD5A2RARBRARGTDP1EPHX2
SCHEMBL195282 0.94 SRD5A2 (0.77) SRD5A2RARBRARGTDP1NPC1
Benzoic Acid SCHEMBL11549239 0.92 SRD5A2 (0.74) SRD5A2RARBRARGTDP1EPHX2
Tert-Butylbenzene SCHEMBL31465191 0.88 SRD5A2 (0.67) SRD5A2RARBRARGTDP1EPHX2
SCHEMBL36693 0.88 SRD5A2 (0.87) SRD5A2RARBRARGTDP1EPHX2
Benzophenone SCHEMBL28080185 0.87 SRD5A2 (0.67) SRD5A2TDP1EPHX2NR1H4NPC1
Hydrochloric Acid SCHEMBL1017064 0.86 SRD5A2 (0.83) SRD5A2RARBRARGTDP1EPHX2
SCHEMBL2778034 0.86 SRD5A2 (0.83) SRD5A2RARBRARGTDP1EPHX2
SCHEMBL592353 0.86 SRD5A2 (0.83) SRD5A2RARBRARGTDP1EPHX2
SCHEMBL205291 0.86 SRD5A2 (0.83) SRD5A2RARBRARGTDP1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260823-B1 IMPROVEMENTS IN OR RELATING TO PRINTING PLATE PRECURSORS E.I. du Pont de Nemours and Company (US) 1993-06-09 EP disclosed
US-4999271-A Photopolymerizable urethane acrylate or methacrylate, lithography VICKERS PLC (GB) 1991-03-12 US disclosed
EP-0260823-A2 Improvements in or relating to printing plate precursors E.I. du Pont de Nemours and Company (US) 1988-03-23 EP disclosed