Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | QDPR | P09417 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12043319 | 1.00 | CHRM2 (0.42) | CHRM2CHRM5CHRM1METTSHR | |
| SCHEMBL12043290 | 0.78 | TSHR (0.40) | METTSHRGABRR1BLMCYP3A4 | |
| SCHEMBL7827160 | 0.76 | — | — | |
| SCHEMBL11081134 | 0.73 | — | — | |
| SCHEMBL9260377 | 0.69 | CHRM2 (0.50) | CHRM2CHRM5CHRM1TSHRBLM | |
| SCHEMBL9260380 | 0.69 | CHRM2 (0.50) | CHRM2CHRM5CHRM1TSHRBLM | |
| SCHEMBL9498303 | 0.69 | — | — | |
| SCHEMBL4875787 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL9257070 | 0.68 | CHRM2 (0.49) | CHRM2CHRM5CHRM1TSHRBLM | |
| Hydrochloric Acid SCHEMBL9257066 | 0.68 | CHRM2 (0.49) | CHRM2CHRM5CHRM1TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271798-B1 | O-SUBSTITUTED TETRAHYDROPYRIDINE OXIME CHOLINERGIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-04-07 | — | — | EP | claimed |