Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31458500 | 1.00 | MEN1 (0.50) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL8158440 | 0.80 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL30592428 | 0.80 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL203781 | 0.78 | PDE10A (0.50) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL1085531 | 0.76 | CYP1A2 (0.65) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL29674708 | 0.76 | CYP1A2 (0.65) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL29674832 | 0.76 | CYP1A2 (0.65) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL12813932 | 0.75 | MEN1 (0.63) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL5260391 | 0.74 | PDE10A (0.62) | MEN1KMT2AALDH1A1MAPTTSHR | |
| Methane SCHEMBL28139150 | 0.74 | MEN1 (0.61) | MEN1KMT2AALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438172-A | HPK1 kinase modulator, preparation method and application thereof | 南京红云生物科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-113717156-B | EGFR inhibitor, preparation method and application thereof | 南京红云生物科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115697996-A | Alkenyl pyrimidine compound, preparation method and application thereof | 南京红云生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113717156-A | EGFR inhibitor, preparation method and application thereof | 南京红云生物科技有限公司 | 2021-11-30 | — | — | CN | disclosed |
| EP-0353531-B1 | HAIR DYE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-5089025-A | HAIR DYE COMPOSITIONS AND CERTAIN 1,2,3,4-TETRAHYDRONITROQUINOXALINES USEFUL THEREIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1992-02-18 | — | — | US | disclosed |
| EP-0426719-A1 | A HAIR DYE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1991-05-15 | — | — | EP | disclosed |
| WO-1990001050-A1 | A HAIR DYE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-02-08 | — | — | WO | disclosed |
| EP-0353531-A1 | Hair dye | Henkel Kommanditgesellschaft auf Aktien (DE) | 1990-02-07 | — | — | EP | disclosed |