Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499689 | 1.00 | FFAR1 (0.47) | FFAR1FFAR4HRH3HSD17B10TSHR | |
| SCHEMBL9499695 | 1.00 | FFAR1 (0.47) | FFAR1FFAR4HRH3HSD17B10TSHR | |
| SCHEMBL9495764 | 0.96 | FFAR1 (0.46) | FFAR1FFAR4HRH3HSD17B10TSHR | |
| SCHEMBL9498151 | 0.96 | FFAR1 (0.46) | FFAR1FFAR4HRH3HSD17B10TSHR | |
| SCHEMBL9495747 | 0.96 | FFAR1 (0.46) | FFAR1FFAR4HRH3HSD17B10TSHR | |
| SCHEMBL9495754 | 0.96 | FFAR1 (0.46) | FFAR1FFAR4HRH3HSD17B10TSHR | |
| SCHEMBL9498148 | 0.96 | FFAR1 (0.46) | FFAR1FFAR4HRH3HSD17B10TSHR | |
| SCHEMBL9498133 | 0.96 | FFAR1 (0.46) | FFAR1FFAR4HRH3HSD17B10TSHR | |
| SCHEMBL10512251 | 0.95 | FFAR1 (0.45) | FFAR1FFAR4HRH3HSD17B10TSHR | |
| SCHEMBL10512245 | 0.95 | FFAR1 (0.45) | FFAR1FFAR4HRH3HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0306505-A1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES. | MERCK PATENT GMBH (DE) | 1989-03-15 | — | — | EP | disclosed |
| WO-1988007523-A1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |