Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496532 | 0.99 | HSD17B10 (0.46) | MCHR1HSD17B10TSHRACACBFFAR1 | |
| SCHEMBL9495618 | 0.99 | HSD17B10 (0.46) | MCHR1HSD17B10TSHRACACBFFAR1 | |
| SCHEMBL9496080 | 0.99 | HSD17B10 (0.46) | MCHR1HSD17B10TSHRACACBFFAR1 | |
| SCHEMBL9498756 | 0.96 | MCHR1 (0.44) | MCHR1HSD17B10TSHRACACBFFAR1 | |
| SCHEMBL9498210 | 0.90 | ACACB (0.50) | MCHR1HSD17B10TSHRACACBFFAR1 | |
| SCHEMBL9854946 | 0.90 | HSD17B10 (0.46) | MCHR1HSD17B10TSHRACACBFFAR1 | |
| SCHEMBL9500122 | 0.90 | ACACB (0.44) | MCHR1ACACBFFAR1FFAR4 | |
| SCHEMBL10511743 | 0.89 | ACACB (0.40) | MCHR1HSD17B10TSHRACACBFFAR1 | |
| SCHEMBL10511905 | 0.89 | ACACB (0.40) | MCHR1HSD17B10TSHRACACBFFAR1 | |
| SCHEMBL10510464 | 0.89 | ACACB (0.40) | MCHR1HSD17B10TSHRACACBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |