Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | RARB | P10826 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500072 | 1.00 | HSD17B10 (0.48) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9498021 | 1.00 | HSD17B10 (0.48) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9498027 | 1.00 | HSD17B10 (0.48) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9496638 | 0.99 | FFAR1 (0.46) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9496651 | 0.99 | FFAR1 (0.46) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9496028 | 0.97 | HSD17B10 (0.51) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9496342 | 0.97 | HSD17B10 (0.51) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9500377 | 0.97 | HSD17B10 (0.51) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9497709 | 0.97 | HSD17B10 (0.51) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9495379 | 0.97 | HSD17B10 (0.51) | HSD17B10TSHRFFAR1FFAR4RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0306505-A1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES. | MERCK PATENT GMBH (DE) | 1989-03-15 | — | — | EP | disclosed |
| WO-1988007523-A1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |