Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | LSS | P48449 | 3/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500078 | 1.00 | FFAR1 (0.38) | FFAR1OPRM1OPRK1OPRL1MAOB | |
| SCHEMBL9497232 | 0.96 | FFAR1 (0.36) | FFAR1OPRM1OPRK1OPRL1MAOB | |
| SCHEMBL9497214 | 0.96 | FFAR1 (0.36) | FFAR1OPRM1OPRK1OPRL1MAOB | |
| SCHEMBL9495580 | 0.92 | LSS (0.37) | FFAR1MAOBP2RY6BACE1LSS | |
| SCHEMBL9495591 | 0.92 | LSS (0.37) | FFAR1MAOBP2RY6BACE1LSS | |
| SCHEMBL9496416 | 0.90 | LSS (0.39) | FFAR1MAOBP2RY6BACE1LSS | |
| SCHEMBL9496412 | 0.90 | LSS (0.39) | FFAR1MAOBP2RY6BACE1LSS | |
| SCHEMBL9497126 | 0.90 | FFAR1 (0.39) | FFAR1MAOBP2RY6BACE1FFAR4 | |
| SCHEMBL9497138 | 0.90 | FFAR1 (0.39) | FFAR1MAOBP2RY6BACE1FFAR4 | |
| SCHEMBL9855586 | 0.89 | FFAR1 (0.45) | FFAR1P2RY6FFAR4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |