Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621583 | 0.88 | KMT2A (0.50) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL43962 | 0.86 | TDP1 (0.72) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL25264 | 0.83 | TDP1 (0.68) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL27551381 | 0.81 | TDP1 (0.66) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL28065040 | 0.81 | TDP1 (0.66) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL28808752 | 0.81 | TDP1 (0.66) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL28080657 | 0.81 | TDP1 (0.83) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL3677745 | 0.81 | TDP1 (0.66) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL1581942 | 0.80 | KMT2A (0.50) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL2464406 | 0.80 | TDP1 (0.74) | TDP1ALDH1A1TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125140-B1 | IMPROVEMENTS IN OR RELATING TO RADIATION SENSITIVE PLATES | VICKERS PLC (GB) | 1988-12-14 | — | — | EP | claimed |
| EP-0125140-A2 | Improvements in or relating to radiation sensitive plates | VICKERS PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0260823-B1 | IMPROVEMENTS IN OR RELATING TO PRINTING PLATE PRECURSORS | E.I. du Pont de Nemours and Company (US) | 1993-06-09 | — | — | EP | disclosed |
| US-4999271-A | Photopolymerizable urethane acrylate or methacrylate, lithography | VICKERS PLC (GB) | 1991-03-12 | — | — | US | disclosed |
| EP-0125140-B1 | IMPROVEMENTS IN OR RELATING TO RADIATION SENSITIVE PLATES | VICKERS PLC (GB) | 1988-12-14 | — | — | EP | disclosed |
| EP-0260823-A2 | Improvements in or relating to printing plate precursors | E.I. du Pont de Nemours and Company (US) | 1988-03-23 | — | — | EP | disclosed |
| EP-0125140-A2 | Improvements in or relating to radiation sensitive plates | VICKERS PLC (GB) | 1984-11-14 | — | — | EP | disclosed |