Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500527 | 1.00 | FFAR1 (0.40) | FFAR1SLC6A3FFAR4KCNH2CYP2C9 | |
| SCHEMBL9246648 | 0.96 | FFAR1 (0.38) | FFAR1SLC6A3FFAR4KCNH2CYP2C9 | |
| SCHEMBL9246645 | 0.96 | FFAR1 (0.38) | FFAR1SLC6A3FFAR4KCNH2CYP2C9 | |
| SCHEMBL9499728 | 0.92 | FFAR1 (0.45) | FFAR1FFAR4KCNH2CYP2C9 | |
| SCHEMBL9855586 | 0.92 | FFAR1 (0.45) | FFAR1FFAR4KCNH2CYP2C9 | |
| SCHEMBL9498796 | 0.91 | KCNH2 (0.39) | FFAR1SLC6A3FFAR4KCNH2 | |
| SCHEMBL9498804 | 0.91 | KCNH2 (0.39) | FFAR1SLC6A3FFAR4KCNH2 | |
| SCHEMBL9499027 | 0.90 | KCNH2 (0.41) | FFAR1SLC6A3FFAR4KCNH2SLC6A2 | |
| SCHEMBL9499025 | 0.90 | KCNH2 (0.41) | FFAR1SLC6A3FFAR4KCNH2SLC6A2 | |
| SCHEMBL9498057 | 0.88 | KCNH2 (0.43) | FFAR1SLC6A3FFAR4KCNH2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |