⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1154959 | 0.69 | — | — | |
| SCHEMBL11222474 | 0.69 | — | — | |
| Methane SCHEMBL8516121 | 0.67 | — | — | |
| SCHEMBL11164627 | 0.67 | — | — | |
| SCHEMBL1259984 | 0.67 | — | — | |
| SCHEMBL3031907 | 0.67 | — | — | |
| SCHEMBL384596 | 0.64 | — | — | |
| SCHEMBL717371 | 0.64 | — | — | |
| Urea SCHEMBL8519968 | 0.62 | — | — | |
| SCHEMBL80456 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173609-B2 | Macrolides useful against inflammatory and allergic diseases | BASILEA PHARMACEUTICA AG (CH) | 2012-05-08 | — | — | US | claimed |
| US-20090069285-A1 | Diphenylazetidinone Derivatives Possessing Cholesterol Absorption Inhibitor Activity | ASTRAZENECA AB (SE) | 2009-03-12 | — | — | US | claimed |
| EP-1699791-A1 | NOVEL TRICYCLIC SPIRODERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2006-09-13 | — | — | EP | claimed |
| WO-2005061499-A1 | NOVEL TRICYCLIC SPIRODERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2005-07-07 | — | — | WO | claimed |
| US-20040043988-A1 | Cycloalkyl alkanoic acids as intergrin receptor antagonists | PHARMACIA CORPORATION | 2004-03-04 | — | — | US | claimed |
| EP-0674176-B1 | Luminescent rhenium complexes and methods of production | IGEN INT INC (US) | 2004-02-04 | — | — | EP | claimed |
| EP-1289960-A2 | CYCLOALKYL ALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | Pharmacia Corporation (US) | 2003-03-12 | — | — | EP | claimed |
| US-20020077321-A1 | Cycloalkyl alkanoic acids as integrin receptor antagonists | PHARMACIA CORPORATION | 2002-06-20 | — | — | US | claimed |
| WO-2001096307-A2 | CYCLOALKYL ALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2001-12-20 | — | — | WO | claimed |
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | claimed |
| JP-1211572-A | — | — | None | — | — | JP | disclosed |
| EP-3355871-A1 | COMBINATIONS OF THE BTK INHIBITOR GS-4059 WITH INHIBITORS SELECTED FROM A JAK, ASK1, BRD AND/OR MMP9 INHIBITOR TO TREAT CANCER, ALLERGIC DISORDERS, AUTOIMMUNE DISEASES OR INFLAMMATORY DISEASES | Gilead Sciences, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-2280948-A1 | PYRIMIDINE, PYRIDINE AND TRIAZINE DERIVATIVES AS MAXI-K CHANNEL OPENERS. | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-02-09 | — | — | EP | disclosed |
| WO-2010130708-A9 | BETA-LACTAMASE INHIBITORS | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2011-01-13 | — | — | WO | disclosed |
| WO-2010130708-A1 | BETA-LACTAMASE INHIBITORS | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2010-11-18 | — | — | WO | disclosed |
| US-5641778-A | EXHIBIT RENIN-INHIBITING PROPERTIES AND CAN BE USED AS ANTIHYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-06-24 | — | — | US | disclosed |
| US-5196546-A | Aphidicides | EASTMAN KODAK COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0442564-A1 | Selective pyrazoline insecticides and fungicides | EASTMAN KODAK COMPANY (US) | 1991-08-21 | — | — | EP | disclosed |
| JP-H01211572-A | PRODUCTION OF HETEROCYCLIC CATION HAVING TROPYLIUM ION SKELETON | FUJI PHOTO FILM CO LTD | 1989-08-24 | — | — | JP | disclosed |
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |