Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5642972 | 0.83 | KMT2A (0.57) | KMT2AMAPTCYP2C19HIF1AOPRM1 | |
| SCHEMBL343793 | 0.77 | KMT2A (0.50) | KMT2AMAPTCYP2C19HIF1AOPRM1 | |
| SCHEMBL11032674 | 0.76 | KMT2A (0.53) | KMT2AMAPTCYP2C19HIF1AOPRM1 | |
| SCHEMBL25049822 | 0.73 | MAPT (0.67) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL6571 | 0.73 | MAPT (0.67) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL29033303 | 0.72 | MAPT (0.64) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| Methyl Alcohol SCHEMBL5282426 | 0.72 | MAPT (0.64) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL27888039 | 0.72 | MAPT (0.64) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL6968554 | 0.72 | MAPT (0.64) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| Hydrogen Peroxide SCHEMBL1652477 | 0.72 | MAPT (0.64) | KMT2AMAPTCYP2C19HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177131-A | Polysilethylenesiloxane, hydrolyzable silane compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |