Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500692 | 0.86 | CDC25B (0.54) | CDC25BPKMLMNAKDM4EGAA | |
| SCHEMBL9195326 | 0.82 | CDC25B (0.73) | CDC25BPKMLMNAKDM4EGAA | |
| SCHEMBL1363387 | 0.80 | CDC25B (0.76) | CDC25BPKMLMNAKDM4EGAA | |
| SCHEMBL6554659 | 0.80 | CDC25B (0.76) | CDC25BPKMLMNAKDM4EGAA | |
| SCHEMBL10607936 | 0.79 | CDC25B (0.41) | CDC25BPKMKDM4EGAAMAPT | |
| SCHEMBL11860250 | 0.79 | CDC25B (0.73) | CDC25BPKMLMNAKDM4EGAA | |
| SCHEMBL23704777 | 0.78 | CDC25B (0.67) | CDC25BPKMLMNAKDM4EGAA | |
| SCHEMBL10954420 | 0.78 | CDC25B (0.67) | CDC25BPKMLMNAKDM4EGAA | |
| SCHEMBL11860246 | 0.77 | CDC25B (0.71) | CDC25BPKMLMNAKDM4EGAA | |
| SCHEMBL3950862 | 0.76 | CDC25B (0.63) | CDC25BPKMLMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312922-B1 | OXETHYLSULFONYL-NITRO- OR -AMINO-BENZOIC ACIDS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0312922-A2 | Oxethylsulfonyl-nitro- or -amino-benzoic acids and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-26 | — | — | EP | disclosed |